For the Quarter Ending September 2025
North America
• In the United States, the Ampicillin Price Index rose in Q3 2025, driven by increased production costs and robust demand.
• Ampicillin production costs increased due to a 2.6% year-over-year PPI rise in August 2025 and higher naphtha costs.
• Demand for Ampicillin was supported by strengthened US pharmaceutical market sentiment and a 5.42% year-over-year retail sales increase.
• Overall chemical manufacturing costs rose in Q3 2025, with CPI rising 3.0% year-over-year in September 2025.
• Industry inventories for chemicals tightened in Q3 2025 due to accelerating destocking, impacting supply.
• US chemical production contracted in Q3 2025, despite 0.1% industrial production growth in September 2025.
• The Ampicillin Price Forecast indicates continued upward pressure due to persistent cost inflation and sustained healthcare demand.
• A low unemployment rate of 4.3% in September 2025 supported healthcare access, bolstering Ampicillin demand.
Why did the price of Ampicillin change in September 2025 in North America?
• Production costs increased due to rising naphtha feedstock and Henry Hub natural gas prices in September 2025.
• Stronger US pharmaceutical market sentiment and health system rebound boosted Ampicillin demand in Q3 2025.
• Tightening industry inventories and contracting US chemical production reduced supply in Q3 2025.
Europe
• In Germany, Ampicillin Price Index rose in Q3 2025, driven by high energy and raw material costs.
• Ampicillin production costs increased due to elevated natural gas and electricity prices across Europe in Q3 2025.
• German chemical industry faced rising input costs, with CPI increasing 2.4% in September 2025, impacting Ampicillin manufacturing.
• Ampicillin demand outlook remains moderately expanding, supported by an aging population and rising chronic diseases.
• The Manufacturing Index was contracting in September 2025, indicating a slowdown in industrial activity affecting chemical demand.
• Industrial production declined 1.0% year-over-year in September 2025, impacting Ampicillin supply chain stability.
• Despite a -1.7% PPI decrease in September 2025, energy cost pressures remained significant for Ampicillin production.
• Ampicillin price forecast reflects sustained cost drivers and moderate pharmaceutical market growth.
Why did the price of Ampicillin change in September 2025 in Europe?
• Elevated natural gas and electricity prices in Europe increased Ampicillin production costs in Q3 2025.
• German chemical industry faced high raw material costs, with CPI increasing 2.4% in September 2025.
• Contracting Manufacturing Index in September 2025 indicated softening industrial demand, influencing Ampicillin.
APAC
• In China, the Ampicillin Price Index fell in Q3 2025, influenced by broader chemical overcapacity and deflationary pressures.
• Ampicillin demand strengthened in Q3 2025, driven by increased reliance on penicillin-based antibiotics and rising healthcare needs.
• Ampicillin production costs faced upward pressure in Q3 2025 due to increased US tariffs on pharmaceutical imports.
• Utility costs for Ampicillin manufacturing rose in Q3 2025, influenced by elevated Brent crude oil prices.
• China's Manufacturing Index was contracting in September 2025, signaling a slowdown in overall industrial activity.
• Industrial production increased by 6.5% year-on-year in September 2025, supporting economic growth.
• The Consumer Price Index (CPI) declined by 0.3% year-on-year in September 2025, indicating deflationary pressures.
• The Producer Price Index (PPI) fell by 2.3% year-on-year in September 2025, suggesting lower factory-gate prices.
Why did the price of Ampicillin change in September 2025 in APAC?
• Increased US tariffs on pharmaceutical imports elevated API input costs in Q3 2025.
• China's broader chemical sector experienced amplified overcapacity during Q3 2025.
• The Consumer Price Index (CPI) declined by 0.3% year-on-year in September 2025.
For the Quarter Ending December 2022
North America
The fourth quarter of 2022 saw changing market trends for Ampicillin Trihydrate API in the North American region. Prices were expected to increase through the second month of the quarter starting with Q4 2022 because of the high cost of manufacturing, numerous logistical issues, and growing inflation.
Rising transportation costs and port congestion at the key ports also helped to keep the market position strong. Due to easing inflation and lowering end-user sector demand on the back of nearing festival season and impeding holidays, prices started to drop later in December 2022. The settlement price for Ampicillin Trihydrate API decreased to USD 45545/MT CFR Los Angeles in the month of December.
APAC
The Asia Pacific region's market for Ampicillin Trihydrate API experienced a volatile trajectory in the fourth quarter of 2022. Starting in Q4 2022, prices were observed to rise through the second month of the quarter due to rising end-user demand and a number of logistical challenges. Additionally, the market scenario was impacted by the tight zero covid rules and frequent lockdowns in the Chinese regions. The market remained competitive due to growing production costs brought on by rising energy costs as well as increased domestic production to fill orders from both local and foreign markets. However, as domestic retailers had sufficient stock on hand later in December, the cost of Ampicillin Trihydrate API decreased. Also, the ease in imports and reduced orders from both domestic and international markets kept weak. During the month of December, the settlement price of Ampicillin Trihydrate API came down to USD 39355/MT FOB Shanghai.
Europe
Ampicillin Trihydrate API pricing in the European region showed a see-saw tendency in the fourth quarter of 2022. The demand for Ampicillin Trihydrate API from the downstream pharmaceutical industry was seen to be steady. The supply chain was impacted by the continuous port congestion and supply disruption in the European region, which resulted in a rise in pricing in the first two months of Q4 2022. A further factor in the elevated trajectory of Ampicillin trihydrate API was the high freight costs. Nevertheless, December sees a price decline as a result of rising stocks and declining end-user sector demand. The settlement price for Ampicillin Trihydrate API dropped to USD 48215/MT CFR Hamburg in December.
For the Quarter Ending September 2022
North America
The prices of Ampicillin Trihydrate in the North American region witnessed a mixed market sentiment during the third quarter of 2022. At the onset of h1 of q3, the prices inclined significantly owing to healthy downstream demand and insufficient supplies with the market participants, which propelled them to increase their quotations. Following the mid-q3, the price declined by 4.91 percent in the domestic market, resulting in stockpiling of inventories with the local suppliers. Additionally, the trading momentum was also on the weaker side owing to the lessened offtakes, which resulted in the accumulation of cargoes in the ports of the United as well as India. Moreover, towards the end of q3, the prices rose again and got settled at USD 44170/MT CFR Los Angeles in the US.
APAC
In the APAC region, the prices of Ampicillin Trihydrate showcase an upsurged price trajectory throughout the third quarter of 2022 due to strong requirements from the pharmaceutical sector. The prices rose in India due to insufficient availability in the domestic market coupled with an incremented downstream demand. Moreover, in terms of supply, the production momentum was halted owing to the maintenance state, which positively supported the market sentiments of Ampicillin Trihydrate. Overall, the cost of Ampicillin Trihydrate witnessed a healthy price sentiment in the q3 and was displayed at INR 2108590/MT Ex-Vapi in the Indian Market with a month-on-month inclination of 4.14 percent.
Europe
The market of Ampicillin Trihydrate mimics a similar trend in North America during the third quarter of 2022 Europe. At the onset of the first half of the third quarter, the prices went on the higher side owing to healthy demand and lessened supplies with the market participants, keeping the prices on the higher side. Additionally, the Russian-Ukraine war and rerouting activities supported the price trends of Ampicillin Trihydrate in Germany. Furthermore, the prices dropped during the second half ofq3 and inclined significantly towards the end of the quarter. Overall, with these mixed sentiments, the prices of Ampicillin Trihydrate demonstrated were assessed at USD 47430/MT CFR Hamburg in Germany.
For the Quarter Ending March 2022
North America
The North American region previously dominated the ampicillin market with surging demand in pharmaceutical industries. The surging incidence of sexually transmitted diseases such as Syphilis and Gonorrhoea in the USA, Canada, and Mexico, has elevated the demand for Ampicillin in this region. The demand for ampicillin antibiotics increased in the first half of Q1 with the increment in the incidence of Covid-19 cases, including pneumonia and acute respiratory tract infection resulting in supply shortage and eventually hiking-up market prices of Ampicillin. By the termination of Q1 2022, the prices remained stagnant as the covid cases started to descend. With surging demand among the end user industries, the prices have showcased upward trend in this quarter. Towards the end of Q2 of 2022, Ampicillin was assessed at USD 44730/MT for CFR Los Angeles during June 2022.
Asia Pacific
In Q1 of 2022, during the first half, the Ampicillin market rose significantly in India, owing to strong demand from the pharmaceutical sector. It is majorly used for curing secondary infections likely pneumonia, acute respiratory tract infection caused due to covid-19. The rising incidence of COVID-19 cases increased the demand for Ampicillin, resulting in increased prices. Also, the occurrence rate of bacterial infection increased with surging temperature, which is anticipated to elevate the demand for Ampicillin. In mid of Q1 2022, the prices subsequently dropped with the decreasing covid cases along with higher inventories as the lockdown disrupted the supply chain. Toward the final weeks of March, the demand again increased with surging covid cases leading to demand supply imbalance. Towards the end of Q2 of 2022, Ampicillin was assessed at USD 1895670/MT for Ex-Vapi during June 2022.
Europe
In Europe, the market growth of Ampicillin has been attributed to increasing prevalence of bacterial infections, including pneumonia. In the first half of Q1 2022, the prices of Ampicillin skyrocketed to record heights owing to the demand side exceeding the supply side of the market with an increasing number of covid cases. Increasing number of antibacterial antibiotic manufacturers and rising awareness among people about infectious diseases is anticipate boosting the ampicillin market. The sales and revenue among major producers of pharmaceutical industries shrank in the first quarter with a revision in the price trend. Port congestions in China imbalanced the supply/demand equilibrium, affecting the European market due to supply shortages. Towards the end of Q2 of 2022, Ampicillin was assessed at USD 46950/MT for CFR Hamburg during June 2022.
